Supplementary Files
Keywords
Computational Fluid Dynamics (CFD)
Finite Element Analysis (FEA)
Magnesium Alloy
Balloon Expansion Analysis
How to Cite
Abstract
Heart diseases are the leading global causes of mortality and morbidity due to obstructed blood vessels. Current clinical practice primarily utilizes stents, but standard models encounter significant limitations, including restenosis, thrombosis, mechanical failure, and issues pertaining to performance and biometric longevity. This research aims to create a novel arterial stent that effectively minimizes vein blockages while enhancing durability and compatibility. with biological environments. The study employs advanced methodologies such as finite element analysis (FEA) and computational fluid dynamics (CFD) simulations to rigorously assess and optimize stent geometry and material characteristics. Key considerations include mechanical stability, decreased restenosis rates, and the potential for controlled degradation using biodegradable materials like magnesium alloys and polymer-metal composites. A magnesium alloy stent model was designed using SolidWorks, followed by three tiers of simulations. After simulating one million cardiac cycles, the stent exhibited fatigue-resilient behaviour in both dynamic linear and nonlinear analyses. The collective results of the simulations affirm that the device achieves high radial strength (~550 N mm?¹), while also offering compliant expansion and effective addressing of the issues surrounding restenosis, thrombosis, and mechanical durability. This innovative approach has the potential to reshape clinical practices, enhance patient outcomes, and establish a benchmark for future stent design research. Future work is suggested to diffuse local stress peaks, alongside outlining a roadmap for transitioning from in vitro and in vivo studies to regulatory approval and subsequent clinical application.
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